Breast Cancer – Causes, Symptoms And Treatment

Breast cancer is a malignant (cancerous) growth that begins in the tissues of the breast. Over the course of a lifetime, one in eight women will be diagnosed with breast cancer. Breast cancer is a cancer of the breast tissue, which can occur in both women and men. Breast cancer may be one of the oldest known forms of cancer tumors in humans.Worldwide, breast cancer is the fifth most common cause of cancer death (after lung cancer, stomach cancer, liver cancer, and colon cancer). Breast cancer kills more women in the United States than any cancer except lung cancer. Today, breast cancer, like other forms of cancer, is considered to be a result of damage to DNA. How this mechanism may occur comes from several known or hypothesized factors (such as exposure to ionizing radiation, or viral mutagenesis). Some factors lead to an increased rate of mutation (exposure to estrogens) and decreased repair (the BRCA1, BRCA2 and p53) genes. Alcohol generally appears to increase the risk of breast cancer.

Breast cancer can also occur in men, although it rarely does. Experts predict 178,000 women and 2,000 men will develop breast cancer in the United States. There are several different types of breast cancer. First is Ductal carcinoma begins in the cells lining the ducts that bring milk to the nipple and accounts for more than 75% of breast cancers. Second is Lobular carcinoma begins in the milk-secreting glands of the breast but is otherwise fairly similar in its behavior to ductal carcinoma. Other varieties of breast cancer can arise from the skin, fat, connective tissues, and other cells present in the breast. Some women have what is known as HER2-positive breast cancer. HER2, short for human epidermal growth factor receptor-2, is a gene that helps control cell growth, division, and repair. When cells have too many copies of this gene, cell growth speeds up.

Causes of Breast Cancer

Simply being a woman is the main risk for breast cancer. While men can also get the disease, it is about 100 times more common in women than in men. The chance of getting breast cancer goes up as a woman gets older. Nearly 8 out of 10 breast cancers are found in women age 50 or older. About 5% to 10% of breast cancers are linked to changes (mutations) in certain genes. The most common gene changes are those of the BRCA1 and BRCA2 genes. Breast cancer risk is higher among women whose close blood relatives have this disease. The relatives can be from either the mother’s or father’s side of the family. Woman with cancer in one breast has a greater chance of getting a new cancer in the other breast or in another part of the same breast. This is different from the first cancer coming back Many experts now believe that the main reason for this is because they have faster growing tumors. Asian, Hispanic, and American Indian women have a lower risk of getting breast cancer. Certain types of abnormal biopsy results can be linked to a slightly higher risk of breast cancer.Women who have had radiation treatment to the chest area (as treatment for another cancer) earlier in life have a greatly increased risk of breast cancer

Some pregnant women were given the drug DES (diethylstilbestrol) because it was thought to lower their chances of losing the baby. Recent studies have shown that these women (and their daughters who were exposed to DES while in the uterus), have a slightly increased risk of getting breast cancer. Use of alcohol is clearly linked to a slightly increased risk of getting breast cancer. Women who have 1 drink a day have a very small increased risk. Those who have 2 to 5 drinks daily have about 1 times the risk of women who drink no alcohol. The American Cancer Society suggests limiting the amount you drink.Being overweight is linked to a higher risk of breast cancer, especially for women after change of life and if the weight gain took place during adulthood. Also, the risk seems to be higher if the extra fat is in the waist area. Breast-feeding and pregnancy: Some studies have shown that breast-feeding slightly lowers breast cancer risk, especially if the breast-feeding lasts 1 to 2 years. This could be because breast-feeding lowers a woman’s total number of menstrual periods, as does pregnancy. Women who began having periods early (before 12 years of age) or who went through the change of life (menopause) after the age of 55 have a slightly increased risk of breast cancer.

Symptoms of Breast Cancer

1.Lumps.

2.Rash.

3.Breast Pain.

4.Cysts.

5.Nipple Discharge.

6.Inverted Nipple.

Treatment of Breast Cancer

1.Hormonal therapy (with tamoxifen).

2.Chemotherapy.

3.Radiotherapy.

4.Surgery.

The Best Designer Board Games

Designer board games are something that is generally considered to have been started in Germany, and while sometimes referred to as German style board games, this title can be misleading. Designer board games have come from nearly every country and all have great success stories in the popularity they enjoy with fans. Many different Americans, for example, have produced vastly popular designer board games. A number of designer board games do come from Germany, however, but despite the intimidating nature of the titles, players should feel comfortable with any of these games. They often are similar to many games that players already know and love, but often present some form of twist or enhancement that can make them even more enjoyable!
Good designer board games all feature some sort of theme which unites the strategy and methods used within the game. Sometimes these themes can seem somewhat bizarre and unsuitable for a game, but that is also part of the charm of the designer game. Once such game, Bohnanza, is technically about bean farming, which causes many a player to raise an eyebrow. However, the real game deals with heavy negotiation and trading between players. By using different cards dealt from the deck, players must plant different bean crops, trade for certain bean crops, and eventually harvest the crops to gain money in return. The player who, at the end of the game, has the largest amount of money wins. While initially sounding a bit ridiculous, Bohnanza provides players with much enjoyment as the strategy needed in the game always changes based on the other players.
Tigris and Euphrates is another designer board game which enjoys much popularity with fans. Based on ancient civilizations, this game gives players the chance to act as neighboring dynasties which are clashing over this region. Players randomly select tiles from a bag and during the game, place these tiles in strategic positions around the board, gaining control of areas to expand their kingdoms. Different tiles stand for different aspects of the game and through careful placement, players can build and strengthen their domains in ways that will reap vast benefits. At the end of the game, players collect points based on the numbers and types of tiles that they have placed, and the player with the largest number of tiles is declared the winner of the game.
Scotland Yard is a designer game that pits one player against the others in a team. One player is designated as “Mr. X,” a fugitive from the law who is running around London, trying to avoid capture. The other players all form the law enforcement team trying to arrest him before a certain time limit has passed and Mr. X can roam free. The board is a map of London, marked with certain transportation routes and all of the stops along those routes. All players are forced to travel along these routes, with Mr. X trying to evade capture while the other players pursue. The twist is that only 3 forms of transportation are available and each one can only be used a certain number of times by the police team.
Much strategy and careful teamwork is required with these games, as with most designer board games. However, with the many different varieties and themes available, it is no wonder that they have become as popular as they are. Everyone should be able to find a game that suits their interests!

Gambling And The 20th Century Rulers Part4

Robert Mugabe
(1924)
Robert Gabriel Mugabe was born on the 21st of February, 1924 in the town of Kutama on the territory of current Zimbabwe. Before coming to power in 1987 he had spent 11 years in prison for participation in the national liberation movement. Robert Mugabe is famous, firstly, for his anti-American claims, as well as for the fact that in 2005 he the inflation reached the record 502% in the new 21st century.

Interestingly, but at the peak of inflation growth speaking in front of the journalists the president of Zimbabwe declared that the population of his country was very happy”. What it meant to be very happy” the president knew not through hearsay. A few years ago Mugabe won the state lottery’s main prize in the amount of 2 639 dollars. Curiously, but only those citizens took part in this lottery who had accounts in the National Bank of Zimbabwe, at this for every 135 dollars there was only one lottery ticket. Naturally, under the name of the current president there was registered the record number of tickets, that is why the prize did not keep him waiting for a long time. They say, the results of the lottery upset the citizens of Zimbabwe very much.
Robert Mugabe is a very temperamental person and a typical gambler by nature. A lot of his statements are made in a burst of passion and excitement. By the way, the attitude of the president towards gambling industry is not in the least bad: there are several casinos opened in the country, as well as race tracks with the totalizator, left to the Zimbabwean from English colonizers.

Augusto Pinochet
(1915)
Augusto Pinochet was born on the 25th of November, 1915, in a Chile resort town of Valparaiso. In September 1973 he organized a putsch against the president of Chile Allende and after his murder took the post of the head of the state. Like many other heroes” of the 20th century, he was distinguished by mass terror in relation to the otherwise-minded”.

General Pinochet was quite a cruel and ruthless person, but under his rule hyperinflation was stopped and economic growth began.

The Chilean dictator had a negative attitude towards gambling industry, and there were no gambling-houses in the country during his rule. However, he had rather a loyal attitude to holding a state lottery. Maybe it was because the control over profits from lotteries was entrusted to his daughter Lucia Pinochet Hiriart?

Only after a few years upon retirement of Pinochet under the president Eduardo Free a new casino was opened in the country in 1997.
At present Augusto Pinochet is in Chile under house arrest and is awaiting the trial for evasion from tax payment. The trial, by the way, perhaps, will not even take place because of his age and extremely bad heath.

We can continue mentioning great dictators and rulers of the 20th century and argue about their attitude to gambling industry. Iosip Broz Tito, Mustafa Kemal Ataturk, Idi Amin, Joseph Desire Mobutu, Muammar Gaddafi, Suharto, Thieu, Somoza, Marcos, Pol Pot, Ceausescu, Bokassa, Hissene Habre, Chombe, Franco, Duvalier, Mengistu Haile Mariam, Batista, Salazar and many others had different attitude to gambling. Some, like Marcos and Batista, liked it a lot, while others, like Gaddafi and Ceausescu, didn’t give it even a chance for existence.
While in Spain all power was in the hands of the general Franco Bahamonde Francisco, people were even afraid of talking about gambling-houses, but as soon as he died and the royal throne was occupied by Juan Carlos I, there were at once opened a number of casinos in the country. While Batista favoured gambling games, Fidel Castro, who substituted him, banned them at once. And it is clear. Batista was an American protg, and Fidel was the one who fought against American imperialism. That is why casinos simply lost favour.

A lot of rulers of the 20th century were quite venturesome personalities having revealed their excitable skills in politics, and not on the cloth of the gambling table in the gambling-house. Who knows, if their passion had been connected with visiting of gambling establishments, perhaps, our planet would be quieter.
Total struggle against gambling in the 20th century was under way only in one, at this the most democratic” country the USA. And after repressions, which failed, gambling industry there not only continued to exist, but started to flourish. The ideas of Marxism-Leninism did not give the right of existence of gambling establishments in the countries that chose the way of rise to radiant future in the form of communism, since the norms of the given ideology prescribed earning money by way of labour, and not in the hours of entertaining pastime. Countries practising traditional Islam do not allow gambling industry on their territory in accordance with their religious dogma. Despite this, Muslim Egypt, Tunis, Morocco and Lebanon have opened gambling-houses. The same was done by the Korean Republic, having demonstrated that ideology is ideology but if the country needs to earn money for the budget, gambling industry won’t hinder it.

Totalitarianism and gambling are not connected with each other in the least. The basis of struggle against gambling industry in 99 cases out of 100 is not the desire to protect the rights and interests of the citizens and the society, but the most trivial desire to win votes of people which any party, striving to come to power, pursues. Politics is rather a subtle thing.